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CURRICULUM VITAE

I.F. DUMITRU

UNIVERSITY PROFESSOR DOCTOR DOCENT IN SCIENCES

LIFE, TEACHING AND SCIENTIFIC ACTIVITY IN CHRONOLOGICAL ORDER

Born at Oarja, Arges district, on the 30th of May 1934;

High-school:              Pitesti, High-school for boys I.C. Bratianu 1941/1952;

Graduate studies:

· University “C.I. Parhon” Bucharest, 1952/1954

· University of Saint-Petersburg, the department of Biochemistry - metabolism, radioactive isotopes, the physiology of the central nervous system, - graduation thesis - “Study of the Regeneration Speed of Cholesterol and the Fraction of the Total Number of Lipids in the Liver both under Normal Circumstances and under the Influence of Hormones (Insulin and Cortisone Acetate)”; June 1958.

· Specialization in the usage of radioactive isotopes both in lab research and in the medical clinic (1954-1958).

· Researcher at the Oncological Institute of Bucharest (10th of September - 1st of December 1958).

Teaching career and other scientific titles:

·  Assistant lecturer 1958-1959 with the Biochemistry Department at the University C.I. Parhon Bucharest.

·  December 1959-January 1963 candidate for a doctor’s degree at the Saint Petersburg University.

·  Ph.D. in Biochemistry -December 1962 with the thesis “The Content and Intensity of the Metabolism of Various Fractions of Phospholipids within the Central Nervous System”.

·  Assistant lecturer- 1963.

·  Lecturer - February 1963- October 1967.

·  Specialization in Enzymology - post doctoral studies at the University of Gand, Belgium, scholarship recipient of king Baudoin the 2nd, under advisor professor Lucien Massart Ph.D. (1963/1964).

·  Temporary reader October 1967.

·  1967-1969 instructor of the Committee on matters of higher education (organization, legislation, development, content, coordination, improvement).

·  Scientific title of doctor docent in sciences (the highest scientific title in Romania) at the University “Alexandru Ioan Cuza” in Iassy, January 1971.

·  Deputy General Director of the General Department of higher education (May 1971- March 1973).

·  Director of the high-school and vocational school education system (October 1973-December 1974).

·  full time reader at the University of Bucharest (October 1973)

·  released from the ministerial position of Director at request (December 1974).

·  Vice-Dean of the Faculty of Biology of the University of Bucharest (January 1977).

·  full time professor of biochemistry at the same faculty (June 1980).

·  Head of the Department of Animal Biology at the Faculty of Biology at the University of Bucharest (March 1985).

·  Granted the right of being advisor to specialized and biochemistry Ph.D. candidates (1980).

·  Head of the Biochemistry Department founded in 1990 (1992-1997).

·  Founder of the team of scientific research and consulting and of the sub-team of Enzymology and Biotechnology along with being appointed 1st degree main researcher and coordinator of research activities (December 1993).

·  Reconfirmation of this appointment in 1996.

·  Setting up of the Centre for Research in Enzymology and Biotechnology (19 executive research positions).

·  appointed as Director of the CREB (July 1996).

·  Reconfirmation of this position in (October 1997, February 1998).

·  Founder and Dean of the faculty of Biotechnology within the Christian-Democrat University “Dimitrie Cantemir” in Bucharest (1991-1995).

Scientific activity in the domains of:

·  The biochemistry of the central nervous system and especially in enzymology (kinetics, separation, purification, molecular mass, crystallization of enzymes, applications in industry and medicine).

·  Founder of the Department for Biochemistry at the University of Bucharest (19740.

·  Founder of post doctoral training courses in biochemistry (1978).

·  Organizer of the first National Conference of Biochemistry in Romania (1970).

·  Editor of the first scientific publication on enzymology in the country “Roumanian Biochemical Letters” (1971) in English.

·  Editor-in-chief of the publication founded in 1996 – present.

·  The Romanian publisher of “The Nomenclature of biochemistry according to the rules designed by IUB / IUPAC” published by The Romanian Academy of Sciences (1984).

·  Coordinating editor of the publication “Roumanian Biotechnological Letters” (1996-present) and of the “Journal of Medicine and Biochemistry” (1997-1999) turned in 2000 into “Journal of Cellular and Molecular Medicine” currently published by the University of Medicine and Pharmacy of Bucharest.

·  Author and co-author, editor and/or coordinator of various publications, books, and papers, as well as teaching and scientific journals, issued both in Romania and abroad.

Titles, diplomas and prizes awarded:

Ř      Diploma of Candidate in Sciences MBL No 001681, Moscow, 13th of March 1963.

Ř      Diploma of the Ministry of Higher Education of the USSR for successfully completing work of scientific research "The Study of the Speed of Renewal of Cholesterol and the Total fraction of Lipids from the Liver under Normal Conditions and under the Influence of the Hormones (Cortisone and Insulin)", February 1967.

Ř      Diploma of Specialization in the use of Radioactive Isotopes in Scientific Research, February 1967.

Ř      The Prize of the Ministry of Education for teaching works (1967).

Ř      The Emil Racovita Prize of the Romanian Academy (1982).

Ř      The Order of Labour (1967).

Ř      University Professor Emeritus (1983).

Member of:

Ř      The society of Physiologists, Biochemists and Pharmacists of the Russian Federation (1958).

Ř      The Biotechnological Society (1960).

Ř      The Belgian Biotechnological Society (1964).

Ř      The Romanian Society of Biological Sciences (1967).

Ř      Deputy chairman of the Romanian Society of Biological Sciences since 1983.

Ř      The Russian Biochemical Society (1993).

Ř      Founding member of the Romanian Biochemical Society (1992).

Ř      UNESCO expert for Ecology and post graduate higher education (1977).

Own treaties, textbooks and scientific papers quoted in specialized literature both in the country and abroad

1)      Lucrari practice de biochimie (i.e. Practical Work in Biochemistry), EDP, Bucharest, Romania, 1967, 319 pages, 208 references.

2)      Vitamine. Chimie, biochimie si fiziologie (i.e. Vitamins. Chemistry, Biochemistry and Physiology), Bucharest University Press, 1970, 190 pages, 22 references.

3)      Hormonii. Structura chimica, biosinteza si aspecte ale actiunii lor fiziologice si biochimice (i.e. Hormones. Chemical structure, biosynthesis and aspects of their physiological and biochemical action), Bucharest University Press, 1970, 139 pages, 17 references.

4)      Biochimie generala cu elemente de biochimie comparata (i.e. General Biochemistry with elements of Comparative Biochemistry), EDP, Bucharest, Romania, 1967, 1973, 536 pages, 265 references, alphabetical index.

5)      Biochimie (i.e. Biochemistry), EDP, Bucharest, Romania, 1980, 928 pages (ample bibliographical references following each chapter, subject index).

6)      Biochimie practica. Proteine si enzime (i.e. Practical Biochemistry. Proteins and Enzymes), Part 1, Bucharest University Press, 1980, 161 pages, 42 references.

7)      Introducere in Enzimologie (i.e. Introduction to Enzymology), Medical Publishing House, Bucharest, Romania, 1981, 624 pages, 1541 references, alphabetical index (together with D.Iordachescu).

8)      Biochimie practica. Aminoacizi, glucide si lipide (i.e. Practical Biochemistry. Aminoacids, sugars and lipids), Part 2, Bucharest University Press, 1982, 131 pages, 30 references (together with D.Iordachescu).

9)      Nomenclatura biochimiei dupa regulile elaborate de IUB-IUPAC (i.e. The Nomenclature of biochemistry according to the rules designed by IUB / IUPAC) Romanian Academy of Sciences, Bucharest 1984, 295 pages, references after each chapter.

10)  Biochimie practica (i.e. Practical Biochemistry), Bucharest University press, 1988, 288 pages, 65 references (together with D.Iordachescu).

11)  Hormonii corpului omenesc, organismelor animale si vegetale (i.e. The Hormones of the Human Body, Animal and Vegetal Organisms), Bucharest University Press, 1989, 373 pages, 1503 references, subject index.

12)  Biotehnologii moderne (i.e. Modern Biotechnologies), Coordinator and author, Technical Publishing House, Bucharest, 1990, 154-200 pages.

13)  Drajdiile, Biotehnologii clasice si moderne (i.e. Yeasts Classic and Modern Biotechnologies), by I.F. Dumitru, Adrian Vamanu, Ovidiu Popa, Bucharest Ars Docendi, 2002, 274 pages, references after each chapter.

EDITOR OF:

Founder and editor of the following periodicals:

1)      Roumanian Biotechnological Letters, Bucharest, Romania, vol. 1-7, 1997-present; a volume is made up of 6 issues).

2)      Journal of Medicine and Biochemistry, an international Journal, Bucharest, Romania, vol. 1-4 (1997-1999), after 2000 renamed into Journal of Cellular and Molecular Medicine, published by UMF Bucharest.

3)      News in Biotechnology, Bucharest, Ilex, 2001, 413 pages, references after each chapter.

4)      Progresses in Biotechnology, Bucharest, Ars Docendi, 449 pages, (together with N. Toma), references after each chapter.

5)      Progresses in Biotechnology, Bucharest, Ars Docendi, vol. 1, 273 pages, (together with Gh. Câmpeanu), references after each chapter.

6)      Progresses in Biotechnology, Bucharest, Ars Docendi, vol. 2, 217 pages, references after each chapter.

Most important accomplishments:

1)      Founder of the higher education in Biochemistry in Romania.

2)      Founder of the Research Centre for Enzymology and Biotechnology at the University of Bucharest.

3)      Well-known researcher in the field of the central nervous system' s biochemistry and in enzymology.

Scientific papers:

over 275 published papers.

In Romania:

Studies, Research in Biochemistry, Rev. Roum. Biol. (published in English), Rom. Journal of Physiology (published in English), Progr. Catal. (published in English), Studies and research in Biology, Rev. Roum. Biochemistry (published in English), Roumanian Biotechnological Letters (published in English), J. Med. Biochemistry (published in English).

Abroad:

Arch. Internat. Physiol. Biochem., Naturwiss, Acta vitamin enzymol., C.R. Acad. Sci. Paris, Comp. Biochem. Physiol., Experientia, Enzymology, Int. J. Biochem., Arch. Biochem. Physiol., Vestnik Leningradskovo Universiteta, and so on.

Scientific papers, monographies, and teaching papers quoted in books, treaties, well-known monographs, international papers that are of reference as well as by various authors from Romania and abroad (in chronological order). The validity of experimental data, of the concepts used and the value of the papers are confirmed by multiple sources.

1)      Enzyme Nomenclature - Recommendation (1978) of the Nomenclature Committee of the International Union of Biochemistry, 1979, Ed. E.C. Webb pages 189, 458.

2)      Enzymes, M. Dixon and E.C. Webb, 1979 - listed in the Russian edition, Izd., 3, 1982 pages 952, 988.

3)      Enzyme Nomenclature, IUB Acad. Press Inc., Ed. E.C. Webb, 1984, mentioned four times.

4)      Enzyme Assays. A Practical Approach by R. Eisenthal and M.J. Dawson, Oxford University Press, 1992, pages 300, 329, 334.

5)      Biochemical Engineering by Harvey W. Blanch, Douglas S. Clark, New York, Basel, Hong Kong, pages 153, 182, 295, 323.

6)      Enzyme Nomenclature, Ed. E.C. Webb, 1992, New Edition, NC-IUBMB by Edwin C. Webb, pages 251, 419, 433, 607, 633 (an enzyme mytilidase - characterized in our laboratory for the first time - is mentioned).

7)      Advances in Cereal Sciences and Technology, Ed. Y. Pomerantz, Minnesota, 1976, pages 342, 371.

8)      Enzyme Nomenclature - Recommendation, (1972) of the International Union of Biochemistry, 1973, Ed. E.C. Webb, pages 157, 339.

9)      Biochimie (i.e. Biochemistry), E. Felszeghy, A. Abraham, Teaching and Pedagogical Publishing House, Bucharest, 1972, page 423.

10)  Metody Opredelenia Radioaktivnovo ugleroda, M.T. Prohorova, Z.N. Tupikova, University Press, Leningrad, 1965, pages 173, 180, 207, 208.

11)  Bolshoy Praktikum po Uglevodnomu i Lipidnomu Obmenu, M.T. Prohorova, Z.N. Tupikova, University Press, Leningrad, 1970, pages 83, 84 (twice), 89, 90 (twice), 207, 208.

12)  Biokhimia Golovnovo Mozaga pri Normalnih i Fiziologiceskih Usloviah, G.S. Haciatrean, Izd. Aiastan, Erevan, 1967, pages 227, 235, 236, 317.

13)  General Chemistry, L. Literat, EDP, Bucharest, Romania, 1975, page 421.

14)  Neirokhimia, Paladin, A.V., Izd. Naukova Dumka, Kiev, 1979, pages 235, 252 (listed with three papers).

15)  Tehnologia produselor de biosinteză (i.e. Technology of Biosynthesis Products), C. Oniscu, Technical Publishing House, 1978, Bucharest, Romania, pages 8, 29, 31, 59, 63, 65, 68, 85, 86, 88, 108, 251, 254, 257, 285.

16)  Elemente de chimie biorganică (i.e. Elements of Bio-inorganic Chemistry), Fl.D. Irimie, Dacia Publishing House, Cluj-Napoca, Romania, 1979, pages 57, 343, 362, 382, 391, 420, 425.

17)  Biologie Celulară (i.e. Cellular Biology), R. Mester, EDP, Bucharest, Romania, page 316 (three synthesis works listed).

18)  Chimie şi biochimie vegetală (i.e. Vegetal Chemistry and Biochemistry), I. Burnea, Ionela Popescu, G. Neamtu, Elena Stancu, S. Lazar, EDP, Bucharest, Romania,1977, page 468.

19)  Lucrări practice de biochimie generală (i.e. Practical Work in General Biochemistry), Simona Ceausescu, Angela Mihaescu, A. Turcu, Magda Petrovan, University Press, Bucharest, Romania, 1981, page 246, (five papers listed).

20)  Electroforeza proteinelor în geluri de poliacrilamidă (i.e. Electrophoresis of Proteins in Polyacrilamid) Jellies, V. Popescu Octavian, Technical Publishing House, Bucharest, Romania, 1990, page 260.

21)  Curs de chimie biologică (i.e. Course in Biological Chemistry), V. Artenie, vol. 1, Iassy, Romania, 1971, page 359 two books listed.

22)  Biochimie medicală (i.e. Medical Biochemistry), S. Capalna, M. Dinu, E. Trutia, EDP, Bucharest, Romania, 1977, page 357.

23)  Biochime vegetală (i.e. Vegetal Biochemistry), G. Neamtu, Ceres Publishing House, Bucharest, 1981, page 431.

24)  Biologie celulară (i.e. Cellular Biology), M. Ionescu-Varo, G. Dimitriu, Cornelia Deliu, EDP, Bucharest, Romania, 1981, page 271.

25)  Investigaţii biochimice (i.e. Biochemical Inquiries), Gh. Nuta, C. Busneag, EDP, Bucharest, Romania, 1977, page 392 (two papers listed).

26)  Explorări biochimice ale organelor interne (i.e. Biochemical Explorations of the Internal Organs), Simona Ceausescu, University Press, Bucharest, Romania, 1981, page 115.

27)  Colagenul şi utilizările lui (i.e. Collagen and its Uses), Gh. Chirita, Technical Publishing House, Bucharest, Romania, 1981, page 155.

28)  Fiziologie vegetală (i.e. Vegetal Physiology), C. Voica, 1982, University Press, Bucharest, Romania, page 368.

29)  Biochimie energetică (i.e. Energetic Biochemistry), C. Turcu, 1982, University Press, Bucharest, Romania, page 207.

30)  Implicaţiile biologice şi medicale ale chimiei anorganice (i.e. Biological and Medical Implications of Inorganic Chemistry), I. Grecu, Maria Neamu, L. Enescu, Junimea Publishing House, Iassy, Romania, 1982, pages 199, 206, 213, 254, 290.

31)  Elemente de biochimie anorganică (i.e. Elements of Bioinorganic Chemistry), M. Strajescu, Felicia Teodor, Dacia Publishing House, Cluj-Napoca, Romania, 1971, pages 57, 343, 362, 382, 391, 420, 425.

32)  Biochimie (i.e. Biochemistry), Matilda Rosetti-Caltoiu, Niculina Mitrea, EDP, Bucharest, Romania, 1985, page 414.

33)  Biochimie medicală şi farmaceutică (i.e. Medical and Pharmaceutical Biochemistry), D. Bedeleanu, I. Manta, Dacia Publishing House, Cluj-Napoca, Romania, 1985, page 494.

34)  Chimie şi Biochimie vegetală (i.e. Vegetal Chemistry and Biochemistry), G. Neamtu, Ionela Popescu, S. Lazar, I. Burnea, I. Brad, Gh. Campeanu, T. Galben, EDP, Bucharest, Romania, 1983, page 481 (two important books listed).

35)  Controlul analitic al proceselor biotehnologice (i.e. The Analytic Control of Biotechnological Processes), by V. Magearu, Technical Publishing House, Bucharest, 1988, page 303, two titles, one monography and one textbook for students.

36)  Biochimie (i.e. Biochemistry), V. Artenie, University Press, Iassy, Romania, 1991, page 398 (two monographies).

37)  Substanţe biologic active din organisme marine (i.e. Active Biological Substances of Marine Organisms), M. Serban and Natalia Rosoiu, Romanian Academy, Bucharest, 1992, pages 96, 97 (listed twice), 104, 107, 118 (one original table reproduced), 122 (three times listed, three original tables reproduced), 123 (three times listed, two original tables reproduced), 124, 125, 159, 163, (four times listed, one original table reproduced), 164 (twice listed, two original tables reproduced), 165 (three times listed, two original tables reproduced), 167 (five times listed, one original table reproduced), 168 (four times listed, one original table reproduced), 169 (five times listed, two original tables reproduced), 170 (four times listed, three original tables reproduced), 171, 195 (scientific papers listed five times), 196 (scientific papers listed four times), 197 (a patent listed.

38)  Biochimie medicală (i.e. Medical Biochemistry), Amon Publishing House, Craiova, Romania, 1994, page 283 (two monographies listed).

39)  Biochimie medicală (i.e. Medical Biochemistry), vol. 1, Universitaria Publishing House, Craiova, Romania, 1997, page 397 (two monographies).

40)  Acidul folic şi derivaţii săi în lumea vie (i.e. Folic Acid and its Derivatives in the Living World), V. Atanasiu, Brilliant Publishing House, Bucharest, Romania, 1997, page 127.

41)  Tratat de biochimie medicală (i.e. Treaty of Medical Biochemistry), Marcela Zamfirescu-Gheorghiu, Aurora Popescu, vol.2, Medical Publishing House, Bucharest, Romania, page 356.

42)  Biochimia sistemului endocrin (i.e. Biochemistry of the Endocrine System), DCSD Publishing House, Craiova, Romania, 1996, page 163.

43)  Biologia moleculară a celulei (i.e. Molecular Biology of the Cell), N. Voiculet, Liliana, Puiu, All Publishing House, Bucharest, Romania, 1997, page 394.

44)  Biotehnologii. Fundamente, Bioreactoare, Enzime (i.e. Biotechnologies. Fundaments, Bioreactors, Enzymes), Stefana Jurcoane, Technical Publishing House, Bucharest, Romania, 200, page 421.

45)  Tendinţe actuale în biotehnologie (i.e. Current Tendencies in Biotechnology), editor G.L. Radu, Ilex Publishing House, Bucharest, 2001, page 294.

46)  Biochimie generală (i.e. General Biochemistry), G. Drochioiu, I. Mangalagiu, I. Druta, Ed. C.E. Demiurg, Iassy, Romania, 2001, page 265.

47)  Progrese în bioanaliză (i.e. Developments in Bio-analysis), editor G.L. Radu, Ars Docendi Publishing House, Bucharest, Romania, 2002, page 289.

48)  Inginerie biochimică şi biotehnologie. 1. Ingineria proceselor biotehnologice (i.e. Biochemical Engineering and Biotechnology. 1. Engineering of Biotechnological Processes), by C. Oniscu and D. Cascaval, Interglobal Publishing House, Iassy, Romania, 2002, page 425.

Papers published in 2001-2002

1)     Dehydrogenase Activity in Carassius carassias white Skeletal muscle, D. Dinu, I.F. Dumitru, M.T. Nechifor Roumanian Biotechnological Letters, 7, (3), 723-728, (2002).

2)     Isolation and Characterization of Two Cathepsins from the Muscle of Carassius auratus gibelio, D. Dinu, I.F. Dumitru, M.T. Nechifor Roumanian Biotechnological Letters, 7, (3), 753-758, (2002).

3)     Biotechnological Studies concerning the obtaining of biomass with probiotic role from yeasts and bacteria, Gh. Campeanu, Vamanu A., Popa O., Dumitru I.F., and others, Roumanian Biotechnological Letters, 7, (4), 795-802, (2002).

4)     Heat Shock Proteins, Nechifor M.T., I.F. Dumitru, Diana Dinu, Roumanian Biotechnological Letters, 7, (5), (2002), in press.

1)      Propolisul şi extractele de propolis (i.e. Propolis and Propolis Extracts), Cristina Mateescu, I.F. Dumitru, News in Biotechnology, Ilex publishing house, Bucharest, Romania, 64-117, (2001).

2)      NAD(P)H oxidaza este o enzimă implicată în stress, creştere celulară şi rezistenţă faţă de antimetaboliţi? (i.e. Is the NAD(P)H oxydase an enzyme involved in stress, cellular growth and resistance to antimetabolites?) Gh. Stoian, I.F. Dumitru, Current Tendencies in Biotechnology, Ilex publishing house, Bucharest, Romania, 359-413, (2001).

3)      Analiza moleculară a alelelor HLA (i.e. Molecular Analysis of HLA Alleles), Cristina Luminita Stanciu, Ioan Florea Dumitru, Current Tendencies in Biotechnology, Ilex publishing house, Bucharest 27-48, (2001).

4)      Metode de marcare radioactiv-neradioactive a biomoleculelor (i.e. Methods Radioactive-Non-radioactive Marking of Biomolecules), Cristina Luminita Stanciu, Ioan Florea Dumitru, Current Tendencies in Biotechnology, Ilex publishing house, Bucharest, 7-26, (2001).

5)      Studii biotehnologice privind obţinerea de biomasă proteică din drojdiile pe substrat C1 şi mixt C1-C6 (i.e. Biotechnological Studies Regarding the Obtaining of Proteic Biomass from Yeasts on a C1 Substrate and on a C1-C6 Mixed Substrate), A. Vamanu, O. Popa, I.F. Dumitru, Gh. Campeanu, Progresses in Biotechnology, Ars Docendi publishing house, Bucharest, 87-114, (2001).

6)      Reducerile compuşilor monocarbonilici mediate de drojdii (i.e. Reductions of Monocarbonilic Components Mediated by Yeasts), O. Popa, I.F. Dumitru, A. Vamanu, Cristina Popa, Gh. Campeanu, Progresses in Biotechnology, Ars Docendi publishing house, Bucharest, 115-135, (2001).

7)      Studii biologice, biotehnologice şi farmacologice privind utilizarea unor produse probiotice (i.e. Biological, Biotechnological and Pharmaceutical Studies Regarding the Use of certain Probiotic Products), A. Vamanu, O.Popa, Gh. Campeanu, I.F. Dumitru, Doina Dobrovolschi, S. Campeanu, E. Vamanu, Carmen Campeanu, Progresses in Biotechnology, Ars Docendi publishing house, Bucharest, 9-26, (2002).

8)      Reducerea cetoesterilor catalizată de drojdii (i.e. Reduction of the Cetoesteres Catalyzed by Yeasts), O. Popa, A. Vamanu, I.F. Dumitru, Gh. Campeanu, Em. Vamanu, Progresses in Biotechnology, Ars Docendi publishing house, Bucharest, 201-217, (2002).

9)      (Drojdiile. Biotehnologii clasice şi moderne (i.e. Yeasts, Classic and Modern Biotechnologies), Ioan Florea Dumitru, Adrian Vamanu, Ovidiu Popa, monograph 274 pages, 7 chapters, bibliography after each chapter, Ars Docendi publishing house, Bucharest, (2002).

N.B. The list of published works in specialized periodicals by my former students, co-workers and my friends that share the same profession, other specialists that I have share the same concerns with have not been the object of the current Curriculum Vitae.

My deepest gratitude and homage to my wife, Biologist-botanist, Professor of Biology VIORICA, my daughters IOANA, Professor of Biology and educational manager, and SANDA-MARIA, pediatrics physician and assistant lecturer at the University of Medicine and Pharmacy of Bucharest for their permanent understanding and moral support.

Bucharest, November 2002

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